The study revealed the unexpected properties of the enzyme that controls the pressure
Angiotensin-converting enzyme (ACE) – an enzyme that circulates in the extracellular space and regulating blood pressure. Ken Bernstein proved that the enzyme plays an important role in regulating the immune system and the blood, affects the development of the kidneys and male reproductive function, says "Remedium".
Experiments with rodents have shown that elevated levels of ACE immune responses body were particularly active. As a result of infectious disease proceeded less rapidly, and in some cases, the immune system even impeded the development of melanoma.
Bernstein also analyzed the impact of ACE on the blood, eliminating the influence of the enzyme on the maturation of red blood cells (were off its encoding genes). As a result, the number of red blood cells and white blood cells were reduced functionality. Moreover, in the absence of ACE in the body of kidney lesions were observed in the structure of the small arteries and kidney tissue itself, which hampered the flow of urine.
Fertility rodents without ACE also questionable. Although sperm continue to develop, the ability to reproduce missing. A suppression of the product of the activity of ACE, angiotensin II had no effect on fertility.