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The study of the transition of the brain in "power save" mode to help in the fight against stroke

The study of the transition of the brain in "power save" mode to help in the fight against stroke

The study of the transition of the brain in "power save" mode to help in the fight against stroke

Brain cells with a lack of energy goes into "power save" mode, and the chemical "switch" serves the same compound as in muscle cells, according to the authors of an article published in the journal Proceedings of the National Academy of Sciences, as quoted by RIA "News".

Most of the energy is constantly necessary brain, is spent on the creation of small electrical discharges of excitation waves passing through the cell membrane in the transmission of nerve signals. Usually circulatory system provides the necessary brain power, but a narrowing or blockage of blood vessels of the brain prevents the normal resursosnabzheniyu.

Mark Evans of the University of Edinburgh and his colleagues studied the mechanism by which the brain protects itself from a lack of energy. Passing in "power save" mode, in which the frequency of nerve impulses is reduced, the brain starts AMFK enzyme which, including regulates energy balance of muscle cells and other cells of the body with heavy loads. "Our results show that if the brain cells do not have enough energy, they start to run slower. But its better to just slower than no," – said one of the researchers, Chris Pearce.

Results can help to create drugs to protect patients at high risk of stroke. The existing drugs that stimulate the production of the enzyme AMFK may be used to prevent stroke.