The inventors have presented the first vaccine fleeing hospital pathogens
British scientists create a vaccine against one of the most dangerous hospital pathogens – C. Difficile, reports The Telegarph. The vaccine can be administered orally as a pill. According to experts, it will be available in the next five years.
Preliminary tests on animals have shown that it is capable of 100% protection from infection. Maximum protection is especially important for people with weakened immune systems, the elderly and children.
Dr Simon Cutting from Royal Holloway University, says, based vaccine is a combination of bacterial spores that live in the intestinal tract of man and C. Difficile. Experts changed Bacillus subtilis, introducing genes C. Difficile. As a result, the key parts of the pathogen have surfaced spores that produce intestinal bacteria.
Disputes in stability, transferring part of the pathogen through the intestinal wall, causing an immune response that protects against future infections. Similar technology could be used to vaccinate against tuberculosis and influenza (nasal spray can).
Currently no vaccine against the pathogen. Moreover, it is rapidly developing resistance to antibiotics. Oral form of the vaccine, according to scientists, has been much more effective than injections. Early next year, is expected to begin testing the vaccine on humans.