Mutation in inhabitants of Asia has helped to create a vaccine against alcoholism
The medicine will be available in two years
Beijing, January 31, PrimaMedia. Researchers from the National University of Chile developed a drug after administration of alcohol consumption which leads directly to a severe hangover. It develops severe nausea, rapid heart rate and general discomfort, according to the portal for physicians MedPro.ru.
The vaccine acts on the body through the antisense RNAs that control the expression of certain genes in the cells of the liver. This breaks the production of the enzyme alcohol dehydrogenase required for the processing of alcohol.
Similarly works disulfiram – a drug for coding of alcoholism. It blocks the transformation of alcohol alcohol dehydrogenase, which leads to an accumulation of acetaldehyde in the blood and the development of alcohol withdrawal syndrome. But by taking disulfiram can unsubscribe at any time, and the action of vaccine lasts for 6 months to 1 year. Before the end of this period, it can not be canceled.
Vaccine developers argue that the basis of the idea of ??a drug investigation are residents of the Far East – Japanese, Chinese and Koreans. 15-20% of them are carriers of mutation, which is slowing down the decay of alcohol in the body.
In the near future, scientists hope to begin preclinical studies of its vaccine in mice. If successful in November 2013 to begin clinical trials of the drug. Ideally, the vaccine could be on the market within two years.
Recall that child alcoholism in Primorye reduce by sober volunteers. A demonstration in the schools of alcohol commercials had a positive effect in Nakhodka and the guerrilla zone.
In addition, from 1 January 2013 in Russia by force of law that restricts the sale of beer at kiosks and pavilions. Restrictions have a positive impact on improving the health of the nation, according to maritime experts.